Brexpiprazole intermediate Powder CAS 70500-72-0
Brexpiprazole intermediate Powder CAS 70500-72-0:
CAS No.: 70500-72-0
Name: 7-Hydroxyquinolinone
Synonyms 7-Hydroxy-2-(1H)-quinolinone; 7-Hydroxycarbostyril; 2,7-Dihydroxyquinoline;
Molecular formula: C9H7NO2
Molecular Weight 161.16
Appearance White Powder
Purity 99% Min
Loss on drying ≤0.5%
Density 1.282g/cm3
M.P. 234-238ºC
B.P. 403.7ºC at 760 mmHg
PSA:53.09000
LogP:1.23370
HS code: 2942000000
Brexpiprazole, sold under the brand name Rexulti, is an atypical antipsychotic. It is a dopamine D2 receptor partial agonistand has been described as a "serotonin–dopamine activity modulator" (SDAM). The drug received FDA approval on July 13, 2015 for the treatment of schizophrenia, and as an adjunctive treatment for depression. It has been designed to provide improved efficacy and tolerability (e.g., less akathisia, restlessness and/or insom…